Author: NP Bate, Ed.S.•Last reviewed: 2026-08-08

All Products

Every research-backed product on this site in one place, grouped by application. We only list products whose ingredients have clinical evidence behind them — nothing here is a miracle cure, and nothing replaces your eye doctor.

4 conditions · 12 products · Affiliate links support the site at no cost to you.

Floaters & PVD

Posterior vitreous detachment—the gel in your eye shrinks and pulls away, leaving clumps that cast shadows.

See the full evidence for Floaters & PVD →
supplement
★★★★☆(210)

VitroCap N

Ankamah et al., TVST 2021;10(12):19. Double-blind RCT in symptomatic floaters: P<0.001 reduction in discomfort and objective opacity area; contrast sensitivity P=0.047. [View study]

$49.90/ 90 servings
Serving:
1 capsule
Key:
L-lysine 125 mg, Vitamin C 40 mg, Vitis vinifera extract 26.3 mg...

Pros

  • Closest match to study protocol
  • Double-blind RCT data
  • Objective opacity reduction outcome

Cons

  • Small trial
  • Not FDA-approved for floaters
  • Single-center study
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supplement
★★★★☆(140)

Bromelain + Papain + Ficin Enzyme Blend

Takeuchi et al., Appl Sci 2020;10(17):5901. Prospective cohort, n=280, 3 months: 65.5–75.5% symptomatic vitreous opacity reduction vs placebo. [View study]

$24.95/ 90 servings
Serving:
1 capsule
Key:
Bromelain 190 mg, Papain 95 mg, Ficin 95 mg

Pros

  • Matches study dosing
  • Largest human cohort in this space
  • Dose-dependent response

Cons

  • No exact branded product match
  • Ficin is rare in commercial blends
  • Open-label design
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supplement
★★★★☆(980)

Curcumin + Piperine Bioavailable Supplement

Malandrini et al., Vision 2025. Pilot study: curcumin-based supplement after Nd:YAG capsulotomy reduced symptomatic floaters and foreign-body sensation. [View study]

$19.99/ 90 servings
Serving:
1 capsule
Key:
Curcumin 1500 mg, Piperine 5 mg

Pros

  • Widely available
  • Bioavailable form
  • Pilot data in post-YAG population

Cons

  • Pilot study only
  • Post-procedure population only
  • Not proven for de novo floaters
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supplement
★★★☆☆(45)

Compounded Atropine 0.01% Drops

Du J, Sabbagh O, Do BK, et al. J Vitreoretin Dis 2025;9(6):831-835. Prospective cohort, n=44, 1 week: 59% satisfaction among completers; pupillary dilation is proposed mechanism. [View study]

$29.99/ 30 servings
Serving:
1 drop
Key:
Atropine sulfate 0.01%

Pros

  • Low concentration profile
  • Symptomatic relief pathway

Cons

  • Off-label use
  • Short study duration
  • Requires compounding pharmacy
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Macular Health (AMD)

Age-related macular degeneration affects the central vision. Early action with the right formula matters.

See the full evidence for Macular Health (AMD) →
supplement
★★★★☆(12,400)

PreserVision AREDS 2 Softgels

The exact vitamin/mineral formula from the NIH AREDS2 trial. Softgels absorb better than tablets. No beta-carotene, so safe for smokers. [View study]

$28.99/ 60 softgels
Serving:
2 softgels
Key:
Lutein 10 mg, Zeaxanthin 2 mg, Zinc 25 mg...

Pros

  • Exact AREDS2 doses
  • Trusted pharma brand (Bausch + Lomb)
  • Take with food (zinc nausea)

Cons

  • Only helps intermediate AMD
  • Large softgels for some
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omega 3
★★★★☆(15,600)

Nordic Naturals Ultimate Omega 2X

High-EPA re-esterified triglyceride (rTG) form, ~70% better absorption than drugstore ethyl ester. IFOS 5-star third-party tested. Matches the ≥2g EPA+DHA dry-eye dose. [View study]

$48.95/ 60 softgels
Serving:
2 softgels
Key:
EPA 1125 mg, DHA 690 mg, Total Omega-3 2150 mg

Pros

  • rTG form = high absorption
  • High EPA:DHA ratio for inflammation
  • Third-party tested (IFOS 5-star)

Cons

  • Pricier than ethyl ester
  • Not a quick fix (6–12 weeks)
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High Eye Pressure (IOP)

Elevated intraocular pressure puts you on the glaucoma-suspect watchlist. Most suspects never develop glaucoma, but IOP is the one risk factor you can influence.

See the full evidence for High Eye Pressure (IOP) →
supplement
★★★★☆(746)

NOW Foods Niacinamide (Vitamin B-3) 500 mg

Nicotinamide (vitamin B3) is the adjunct with the strongest emerging neuroprotection data: a Phase 2 RCT (n=42, De Moraes, JAMA Ophthalmol 2022) improved visual field vs placebo, and a crossover RCT (n=57) improved inner retinal function on ERG (Hui, Clin Exp Ophthalmol 2020). It does NOT lower IOP — the goal is protecting the optic nerve. Trial dose is 3 g/day = 6 of these capsules, far above the RDA — discuss with your doctor first. [View study]

$7.95/ 100 servings
Serving:
1 capsule
Key:
Niacinamide (B-3) 500 mg

Pros

  • Cheap — the 3 g trial dose costs pennies a day
  • Niacinamide form doesn't cause the niacin flush
  • NOW is third-party tested

Cons

  • Neuroprotection only — does NOT lower IOP
  • Trial dose is 6 capsules/day, far above RDA
  • Discuss with your ophthalmologist first
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supplement
★★★★☆(1,156)

Life Extension Eye Pressure Support with Mirtogenol

Mirtogenol is the patented pine bark + bilberry combination studied in ocular hypertension: modest IOP reduction (~3 mmHg over 3 months) and possible potentiation of latanoprost (Steigerwalt, Mol Vis 2008; Clin Ophthalmol 2010). Small trials, mostly one research group — treat as adjunctive, not a replacement for monitoring or drops. [View study]

$25.49/ 30 servings
Serving:
1 capsule
Key:
Bilberry extract 80 mg, French maritime pine bark 40 mg

Pros

  • Matches the studied Mirtogenol dosing
  • Life Extension holds the Mirtogenol license
  • May add to latanoprost effect

Cons

  • Small trials, mostly one research group
  • ~3 mmHg is modest — won't replace drops
  • Talk to your doctor before starting
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supplement
★★★★☆(415)

Nootropics Depot High Potency Saffron Extract (30 mg)

The studied dose is 30 mg/day saffron extract, and this product is standardized to ≥7.5% crocins to match it. One small RCT in POAG patients on drops found added modest IOP reduction (Jabbarpoor Bonyadi, BMC Complement Altern Med 2014). Single trial. [View study]

$26.99/ 60 servings
Serving:
1 capsule
Key:
Saffron extract 30 mg, Crocins ≥7.5%, Safranals ≥1%

Pros

  • Exact 30 mg studied dose
  • Standardized to ≥7.5% crocins
  • Third-party tested

Cons

  • Single small RCT
  • Pricier than generic saffron
  • Doesn't replace monitoring or drops
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supplement
★★★★☆(2,562)

Jarrow Formulas Citicoline (CDP-Choline) 250 mg

The 2023 systematic review/meta-analysis found no significant effect of citicoline on IOP, visual field, or retinal nerve fiber preservation; some individual trials show hopeful visual-function signals, but the pooled evidence says no. We're including this as some individual trials showed hopeful signals. [View study]

$44.94/ 120 servings
Serving:
1 capsule
Key:
Citicoline (CDP-choline) 250 mg

Pros

  • Established brand, good value per serving
  • Trial range 500–1000 mg/day = 2–4 capsules
  • Third-party tested

Cons

  • Pooled meta-analysis: no significant effect
  • Skeptical verdict, not a proven IOP treatment
  • Discuss with your doctor
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Dry Eye & Discomfort

Burning, gritty, blurry vision, especially after screens. Usually evaporative dry eye from clogged oil glands (MGD).

See the full evidence for Dry Eye & Discomfort →
omega 3
★★★★☆(15,600)

Nordic Naturals Ultimate Omega 2X

High-EPA re-esterified triglyceride (rTG) form, ~70% better absorption than drugstore ethyl ester. IFOS 5-star third-party tested. Matches the ≥2g EPA+DHA dry-eye dose. [View study]

$48.95/ 60 softgels
Serving:
2 softgels
Key:
EPA 1125 mg, DHA 690 mg, Total Omega-3 2150 mg

Pros

  • rTG form = high absorption
  • High EPA:DHA ratio for inflammation
  • Third-party tested (IFOS 5-star)

Cons

  • Pricier than ethyl ester
  • Not a quick fix (6–12 weeks)
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artificial tear
★★★★☆(8,700)

Systane Complete PF

Nano-droplet lipid technology that spreads evenly over the tear film. Preservative-free single-use vials. Alcon trials show improved tear breakup time (TBUT) for mixed dry eye. [View study]

$24.99/ 30 servings
Serving:
1 vial
Key:
Lipid nano-droplet, Preservative none (PF), Type mixed dry eye

Pros

  • Nano-lipid spreads evenly
  • Preservative-free
  • Alcon = eye-care specialist

Cons

  • Single-use only (more waste)
  • Vials not refillable
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artificial tear
★★★★☆(5,400)

Refresh Mega-3 Advanced

Lipid-enhanced artificial tear with flaxseed oil (omega-3) to stabilize the tear film. Good daytime option alongside warm compresses for evaporative dry eye (MGD). [View study]

$19.99/ 30 servings
Serving:
1 vial
Key:
Flaxseed oil omega-3, Preservative none (PF), Type evaporative dry eye

Pros

  • Lipid + omega-3 formula
  • Preservative-free vials
  • Budget-friendly

Cons

  • Mild film blur for some
  • Less potent than prescription drops
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